Antineovascular therapy with angiogenic vessel-targeted polyethyleneglycol-shielded liposomal DPP–CNDAC
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چکیده
منابع مشابه
Chronopharmacologic cancer treatment with an angiogenic vessel-targeted liposomal drug.
Antineovascular therapy (ANET), which eradicates angiogenic endothelial cells by specifically delivered anticancer drugs to tumor cells to obtain complete cutoff of blood supply, is an effective modality for cancer treatment. Since the expression of vascular endothelial growth factor (VEGF) in hypoxic tumor cells is known to fluctuate in a circadian oscillation, we investigated the chronopharma...
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NAOTO OKU, TOMOHIRO ASAI, KOHTA KUROHANE, KOH WATANABE, KOICHI KUROMI, YUKIHIRO NAMBA, KOICHI OGINO and TAKAO TAKI Department of Medical Biochemistry, School of Pharmaceutical Sciences, University of Shizuoka, Yada, Shizuoka 422-8526 Japan; Nippon Fine Chemical Co. Ltd., Takasago, Hyogo 676-0074, Japan; and Molecular Medical Science Institute, Otsuka Pharmaceutical Co., Ltd., Kagasuno, Kawauchi...
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Cancer photodynamic therapy (PDT) with benzoporphyrin derivative monoacid ring A (BPD-MA, verteporfin) may be effective not only by being directly cytotoxic to tumor cells, but also by being cytotoxic to the endothelium of tumor neovasculature. In the present study, we investigated the effect of PDT with an experimental liposomal formulation of BPD-MA on tumor-induced angiogenic vessels using a...
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Immunosuppressive agents are used for the treatment of immune-mediated myocarditis; however, the need to develop a more effective therapeutic approach remains. Nano-sized liposomes may accumulate in and selectively deliver drugs to an inflammatory lesion with enhanced vascular permeability. The aims of this study were to investigate the distribution of liposomal FK506, an immunosuppressive drug...
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ژورنال
عنوان ژورنال: Cancer Science
سال: 2008
ISSN: 1347-9032,1349-7006
DOI: 10.1111/j.1349-7006.2008.00758.x